Ida Sim, PhD, MD

Education
1997 - Fellowship, Health Services Research, Stanford University
PhD, 1997 - Medical Informatics, Stanford University
1993 - Primary Care Internal Medicine Residency, Massachussetts General Hospital
M.D., 1990 - , Stanford University
Honors and Awards
  • STATUS2024 Health Science Leader, STAT News, 2024
  • Elected Member, National Academy of Medicine, 2022
  • Elected Member, American Society for Clinical Investigation, 2010
  • Elected Fellow, American College of Medial Informatics, 2007
  • Leadership Award, American Medical Informatics Association, 2005
  • United States Presidential Early Career Award for Scientists and Engineers, White House Office of Science Technology and Policy, 2000
Websites
Publications
  1. Block VJ, Koshal K, Wijangco J, Miller N, Sara N, Henderson K, Reihm J, Gopal A, Mohan SD, Gelfand JM, Guo CY, Oommen L, Nylander A, Rowson JA, Brown E, Sanders S, Rankin K, Lyles CR, Sim I, Bove R.. A Closed-Loop Falls Monitoring and Prevention App for Multiple Sclerosis Clinical Practice: Human-Centered Design of the Multiple Sclerosis Falls InsightTrack. JMIR Human Factors 2024. PMID: 38206662


  2. Arvisais-Anhalt S, Ravi A, Weia B, Aarts J, Ahmad HB, Araj E, Bauml JA, Benham-Hutchins M, Boyd AD, Brecht-Doscher A, Butler-Henderson K, Butte A, Cardillo AB, Chilukuri N, Cho MK, Cohen JK, Craven CK, Crusco SJ, Dadabhoy F, Dash D, DeBolt C, Elkin PL, Fayanju OA, Fochtmann L, Graham JV, Hanna J, Hersh W, Hoffard MR, Hron J, Huang SS, Jackson BR, Kaplan B, Kelly W, Ko K, Koppel R, Kurapati N, Labbad G, Lee J, Lehmann CU, Leitner S, Liao ZC, Medford RJ, Melnick ER, Muniyappa AN, Murray S, Neinstein A, Nichols-Johnson V, Novak L, Ogan WS, Ozeran L, Pageler N, Pandita D, Perumbeti A, Petersen C, Pierce L, Puttagunta R, Ramaswamy P, Rogers KM, Rosenbloom T, Ryan A, Saleh S, Sarabu C, Schreiber R, Shaw KA, Sim I, Sirintrapun SJ, Solomonides A, Spector JD, Starren JB, Stoffel M, Subbian V, Swanson K, Tomes A, Trang K, Unertl KM, Weon JL, Whooley M, Wiley K, Williamson DF, Winkelstein P, Wong J, Xie J, Yarahuan JKW, Yung N, Zera C, Ratanawongsa N, Sadasivaiah S.. Paging the Clinical Informatics Community: Respond STAT to Dobbs v Jackson's Women's Health Organization. Applied clinical informatics 2022. PMID: 36535703


  3. Ida Sim, Marina Sirota.. Data and Computation: A Contemporary Landscape. Intelligent Systems in Medicine and Health 2022. PMID:


  4. Liu H, Carini S, Chen Z, Phillips Hey S, Sim I, Weng C.. Ontology-based categorization of clinical studies by their conditions. Journal of biomedical informatics 2022. PMID: 36283581


  5. Duan N, Norman D, Schmid C, Sim I, Kravitz RL.. Personalized Data Science and Personalized (N-of-1) Trials: Promising Paradigms for Individualized Health Care. Harvard data science review 2022. PMID: 38009133


  6. Horwitz RI, Hayes-Conroy A, Singer BH, Cullen MR, Badal K, Sim I.. Falling down the biological rabbit hole: Epstein-Barr virus, biography, and multiple sclerosis. The Journal of clinical investigation 2022. PMID: 36047497


  7. Ida Sim.. Data Sharing and Reuse. 2022. PMID:


  8. Horwitz RI, Conroy AH, Cullen MR, Colella K, Mawn M, Singer BH, Sim I.. Long COVID and Medicine's Two Cultures. The American journal of medicine 2022. PMID: 35417745


  9. Larson K, Sim I, von Isenburg M, Levenstein M, Rockhold F, Neumann S, D'Arcy C, Graham E, Zuckerman D, Li R.. COVID-19 interventional trials: Analysis of data sharing intentions during a time of pandemic. Contemporary clinical trials 2022. PMID: 35182738


  10. Zeng B, Bove R, Carini S, Lee JS, Pollak JP, Schleimer E, Sim I.. Standardized Integration of Person-Generated Data Into Routine Clinical Care. JMIR mHealth and uHealth 2022. PMID: 35142627


  11. Horwitz RI, Singer BH, Hayes-Conroy A, Cullen MR, Mawn M, Colella K, Sim I.. Biosocial Pathogenesis. Psychotherapy and psychosomatics 2022. PMID: 35104822


  12. Marcus GM, Modrow MF, Schmid CH, Sigona K, Nah G, Yang J, Chu TC, Joyce S, Gettabecha S, Ogomori K, Yang V, Butcher X, Hills MT, McCall D, Sciarappa K, Sim I, Pletcher MJ, Olgin JE.. Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation: The I-STOP-AFib Randomized Clinical Trial. JAMA cardiology 2022. PMID: 34775507


  13. Wang EY, Breyer BN, Lee AW, Rios N, Oni-Orisan A, Steinman MA, Sim I, Kenfield SA, Bauer SR.. Perceptions of Older Men Using a Mobile Health App to Monitor Lower Urinary Tract Symptoms and Tamsulosin Side Effects: Mixed Methods Study. JMIR Human Factors 2021. PMID: 34951599


  14. Lee AW, Kenfield SA, Wang EY, Enriquez A, Oni-Orisan A, Steinman MA, Sim I, Breyer BN, Bauer SR.. Tracking Lower Urinary Tract Symptoms and Tamsulosin Side Effects Among Older Men Using a Mobile App (PERSONAL): Feasibility and Usability Study. JMIR formative research 2021. PMID: 34889745


  15. Horwitz RI, Lobitz G, Mawn M, Conroy AH, Cullen MR, Sim I, Singer BH.. Rethinking Table 1. Journal of clinical epidemiology 2021. PMID: 34800675


  16. Sim I, Cassel C.. HIPAA and the Leak of "Deidentified" EHR Data. The New England journal of medicine 2021. PMID: 34525298


  17. Elizabeth Y. Wang, Benjamin N. Breyer, Austin Lee, Natalie Rios, Akinyemi Oni-Orisan, Michael A. Steinman, Ida Sim, Stacey A. Kenfield, Scott R. Bauer.. MP28-03 PERCEPTIONS OF OLDER MEN USING A MOBILE HEALTH APPLICATION TO MONITOR LOWER URINARY TRACT SYMPTOMS AND TAMSULOSIN ADVERSE EFFECTS: MIXED-METHODS STUDY. Investigative Urology 2021. PMID:


  18. Kravitz RL, Marois M, Sim I, Ward D, Kanekar SS, Yu A, Dounias P, Yang J, Wang Y, Schmid CH.. Chronic pain treatment preferences change following participation in N-of-1 trials, but not always in the expected direction. Journal of clinical epidemiology 2021. PMID: 34400254


  19. Horwitz RI, Lobitz G, Mawn M, Conroy AH, Cullen MR, Sim I, Singer BH.. Biosocial medicine: Biology, biography, and the tailored care of the patient. SSM - Population Health 2021. PMID: 34430699


  20. Coetzee T, Ball MP, Boutin M, Bronson A, Dexter DT, English RA, Furlong P, Goodman AD, Grossman C, Hernandez AF, Hinners JE, Hudson L, Kennedy A, Marchisotto MJ, Matrisian L, Myers E, Nowell WB, Nosek BA, Sherer T, Shore C, Sim I, Smolensky L, Williams C, Wood J, Terry SF.. Correction: Data Sharing Goals for Nonprofit Funders of Clinical Trials. Journal of participatory medicine 2021. PMID: 34255670


  21. Ku JP, Sim I.. Mobile Health: making the leap to research and clinics. NPJ digital medicine 2021. PMID: 33990671


  22. Coetzee T, Ball MP, Boutin M, Bronson A, Dexter DT, English RA, Furlong P, Goodman AD, Grossman C, Hernandez AF, Hinners JE, Hudson L, Kennedy A, Marchisotto MJ, Myers E, Nowell WB, Nosek BA, Sherer T, Shore C, Sim I, Smolensky L, Williams C, Wood J, Terry SF, Matrisian L.. Data Sharing Goals for Nonprofit Funders of Clinical Trials. Journal of participatory medicine 2021. PMID: 33779573


  23. Li R, von Isenburg M, Levenstein M, Neumann S, Wood J, Sim I.. COVID-19 trials: declarations of data sharing intentions at trial registration and at publication. Trials 2021. PMID: 33602275


  24. Bent B, Sim I, Dunn JP.. Digital Medicine Community Perspectives and Challenges: Survey Study. JMIR mHealth and uHealth 2021. PMID: 33533721


  25. Li R, Wood J, Baskaran A, Neumann S, Graham E, Levenstein M, Sim I.. Timely access to trial data in the context of a pandemic: the time is now. BMJ open 2020. PMID: 33122319


  26. Lo B, Sim I.. Ethical Framework for Assessing Manual and Digital Contact Tracing for COVID-19. Annals of internal medicine 2020. PMID: 33076694


  27. Kury F, Butler A, Yuan C, Fu LH, Sun Y, Liu H, Sim I, Carini S, Weng C.. Chia, a large annotated corpus of clinical trial eligibility criteria. Scientific data 2020. PMID: 32855408


  28. Bent B, Wang K, Grzesiak E, Jiang C, Qi Y, Jiang Y, Cho P, Zingler K, Ogbeide FI, Zhao A, Runge R, Sim I, Dunn J.. The digital biomarker discovery pipeline: An open-source software platform for the development of digital biomarkers using mHealth and wearables data. Journal of clinical and translational science 2020. PMID: 33948242


  29. Bauer SR, Breyer BN, Oni-Orisan A, Steinman MA, Sim I, McCulloch CE, Kenfield SA.. PERSONAL: Feasibility Study Protocol for Placebo-Controlled, Randomized n-of-1 Trials of Tamsulosin for Lower Urinary Tract Symptoms. Frontiers in Digital Health 2020. PMID: 34713020


  30. Kravitz RL, Aguilera A, Chen EJ, Choi YK, Hekler E, Karr C, Kim KK, Phatak S, Sarkar S, Schueller SM, Sim I, Yang J, Schmid CH.. Feasibility, Acceptability, and Influence of mHealth-Supported N-of-1 Trials for Enhanced Cognitive and Emotional Well-Being in US Volunteers. Frontiers in public health 2020. PMID: 32695740


  31. Ida Sim.. Data Sharing and Reuse. Principles and Practice of Clinical Trials 2020. PMID:


  32. Sim I, Stebbins M, Bierer BE, Butte AJ, Drazen J, Dzau V, Hernandez AF, Krumholz HM, Lo B, Munos B, Perakslis E, Rockhold F, Ross JS, Terry SF, Yamamoto KR, Zarin DA, Li R.. Time for NIH to lead on data sharing. Science (New York, N.Y.) 2020. PMID: 32193313


  33. Sim I.. Mobile Devices and Health. The New England journal of medicine 2019. PMID: 31483966


  34. Li R, Sim I.. How Clinical Trial Data Sharing Platforms Can Advance the Study of Biomarkers. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2019. PMID: 31560635


  35. Odineal DD, Marois MT, Ward D, Schmid CH, Cabrera R, Sim I, Wang Y, Wilsey B, Duan N, Henry SG, Kravitz RL.. Effect of Mobile Device-Assisted N-of-1 Trial Participation on Analgesic Prescribing for Chronic Pain: Randomized Controlled Trial. Journal of general internal medicine 2019. PMID: 31463686


  36. Hekler EB, Klasnja P, Chevance G, Golaszewski NM, Lewis D, Sim I.. Why we need a small data paradigm. BMC medicine 2019. PMID: 31311528


  37. Li T, Saldanha IJ, Jap J, Smith BT, Canner J, Hutfless SM, Branch V, Carini S, Chan W, de Bruijn B, Wallace BC, Walsh SA, Whamond EJ, Murad MH, Sim I, Berlin JA, Lau J, Dickersin K, Schmid CH.. A randomized trial provided new evidence on the accuracy and efficiency of traditional vs. electronically annotated abstraction approaches in systematic reviews. Journal of clinical epidemiology 2019. PMID: 31302205


  38. Zhang X, Hailu B, Tabor DC, Gold R, Sayre MH, Sim I, Jean-Francois B, Casnoff CA, Cullen T, Thomas VA, Artiles L, Williams K, Le PT, Aklin CF, James R.. Role of Health Information Technology in Addressing Health Disparities: Patient, Clinician, and System Perspectives. Medical care 2019. PMID: 31095049


  39. Kravitz RL, Sim I, Duan N.. A Case for n-of-1 Trials-Reply. JAMA internal medicine 2019. PMID: 30830192


  40. Kravitz RL, Schmid CH, Sim I.. Finding Benefit in n-of-1 Trials-Reply. JAMA internal medicine 2019. PMID: 30830195


  41. Fukushima M, Austin C, Sato N, Maruyama T, Navarro E, Rocca M, Demotes J, Haendel M, Volchenboum SL, Cowperthwaite M, Silverstein JC, Webb C, Sim I, Chase M, Speakman J, Augustine E, Ford DE, Kush R.. The Global academic research organization network: Data sharing to cure diseases and enable learning health systems. Learning health systems 2018. PMID: 31245596


  42. Rebecca Li, Jessica Scott, Frank Rockhold, Nina Hill, Julie Wood, Ida Sim.. Moving Data Sharing Forward: The Launch of the Vivli Platform. NAM Perspectives 2018. PMID:


  43. Whitney RL, Ward DH, Marois MT, Schmid CH, Sim I, Kravitz RL.. Patient Perceptions of Their Own Data in mHealth Technology-Enabled N-of-1 Trials for Chronic Pain: Qualitative Study. JMIR mHealth and uHealth 2018. PMID: 30309834


  44. Kravitz RL, Schmid CH, Marois M, Wilsey B, Ward D, Hays RD, Duan N, Wang Y, MacDonald S, Jerant A, Servadio JL, Haddad D, Sim I.. Effect of Mobile Device-Supported Single-Patient Multi-crossover Trials on Treatment of Chronic Musculoskeletal Pain: A Randomized Clinical Trial. JAMA internal medicine 2018. PMID: 30193253


  45. Kumar S, Abowd G, Abraham WT, al'Absi M, Chau DHP, Ertin E, Estrin D, Ganesan D, Hnat T, Hossain SM, Ives Z, Kerr J, Marlin BM, Murphy S, Rehg JM, Nahum-Shani I, Shetty V, Sim I, Spring B, Srivastava M, Wetter D.. Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K). IEEE pervasive computing 2017. PMID: 29276451


  46. Saldanha IJ, Schmid CH, Lau J, Dickersin K, Berlin JA, Jap J, Smith BT, Carini S, Chan W, De Bruijn B, Wallace BC, Hutfless SM, Sim I, Murad MH, Walsh SA, Whamond EJ, Li T.. Evaluating Data Abstraction Assistant, a novel software application for data abstraction during systematic reviews: protocol for a randomized controlled trial. Systematic reviews 2016. PMID: 27876082


  47. Bierer BE, Li R, Barnes M, Sim I.. A Global, Neutral Platform for Sharing Trial Data. The New England journal of medicine 2016. PMID: 27168194


  48. Sim I.. Two Ways of Knowing: Big Data and Evidence-Based Medicine. Annals of internal medicine 2016. PMID: 26809201


  49. He Z, Ryan P, Hoxha J, Wang S, Carini S, Sim I, Weng C.. Multivariate analysis of the population representativeness of related clinical studies. Journal of biomedical informatics 2016. PMID: 26820188


  50. Elliott JH, Grimshaw J, Altman R, Bero L, Goodman SN, Henry D, Macleod M, Tovey D, Tugwell P, White H, Sim I.. Informatics: Make sense of health data. Nature 2015. PMID: 26536942


  51. Kumar S, Abowd GD, Abraham WT, al'Absi M, Beck JG, Chau DH, Condie T, Conroy DE, Ertin E, Estrin D, Ganesan D, Lam C, Marlin B, Marsh CB, Murphy SA, Nahum-Shani I, Patrick K, Rehg JM, Sharmin M, Shetty V, Sim I, Spring B, Srivastava M, Wetter DW.. Center of excellence for mobile sensor data-to-knowledge (MD2K). Journal of the American Medical Informatics Association : JAMIA 2015. PMID: 26555017


  52. Barr C, Marois M, Sim I, Schmid CH, Wilsey B, Ward D, Duan N, Hays RD, Selsky J, Servadio J, Schwartz M, Dsouza C, Dhammi N, Holt Z, Baquero V, MacDonald S, Jerant A, Sprinkle R, Kravitz RL.. The PREEMPT study - evaluating smartphone-assisted n-of-1 trials in patients with chronic pain: study protocol for a randomized controlled trial. Trials 2015. PMID: 25881274


  53. He Z, Carini S, Sim I, Weng C.. Visual aggregate analysis of eligibility features of clinical trials. Journal of biomedical informatics 2015. PMID: 25615940


  54. Ross J, Neylan T, Weiner M, Chao L, Samuelson K, Sim I.. Towards Constructing a New Taxonomy for Psychiatry Using Self-reported Symptoms. Studies in health technology and informatics 2015. PMID: 26262149


  55. He Z, Carini S, Hao T, Sim I, Weng C.. A method for analyzing commonalities in clinical trial target populations. AMIA ... Annual Symposium proceedings. AMIA Symposium 2014. PMID: 25954450


  56. Brennan PF, Valdez R, Alexander G, Arora S, Bernstam EV, Edmunds M, Kirienko N, Martin RD, Sim I, Skiba D, Rosenbloom T.. Patient-centered care, collaboration, communication, and coordination: a report from AMIA's 2013 Policy Meeting. Journal of the American Medical Informatics Association : JAMIA 2014. PMID: 25359545


  57. DePasse JW, Chen CE, Sawyer A, Jethwani K, Sim I.. Academic Medical Centers as digital health catalysts. Healthcare (Amsterdam, Netherlands) 2014. PMID: 26250503


  58. Sim I, Tu SW, Carini S, Lehmann HP, Pollock BH, Peleg M, Wittkowski KM.. The Ontology of Clinical Research (OCRe): an informatics foundation for the science of clinical research. Journal of biomedical informatics 2013. PMID: 24239612


  59. Roumiantseva D, Carini S, Sim I, Wagner TH.. Sponsorship and design characteristics of trials registered in ClinicalTrials.gov. Contemporary clinical trials 2013. PMID: 23380028


  60. Ochs C, Agrawal A, Perl Y, Halper M, Tu SW, Carini S, Sim I, Noy N, Musen M, Geller J.. Deriving an abstraction network to support quality assurance in OCRe. AMIA ... Annual Symposium proceedings. AMIA Symposium 2012. PMID: 23304341


  61. Sim I, Carini S, Tu SW, Detwiler LT, Brinkley J, Mollah SA, Burke K, Lehmann HP, Chakraborty S, Wittkowski KM, Pollock BH, Johnson TM, Huser V, Human Studies Database Project.. Ontology-based federated data access to human studies information. AMIA ... Annual Symposium proceedings. AMIA Symposium 2012. PMID: 23304360


  62. Chen C, Haddad D, Selsky J, Hoffman JE, Kravitz RL, Estrin DE, Sim I.. Making sense of mobile health data: an open architecture to improve individual- and population-level health. Journal of medical Internet research 2012. PMID: 22875563


  63. Boland MR, Tu SW, Carini S, Sim I, Weng C.. EliXR-TIME: A Temporal Knowledge Representation for Clinical Research Eligibility Criteria. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 2012. PMID: 22779055


  64. Ida Sim, Joyce C. Niland.. Study Protocol Representation. Clinical Research Informatics 2012. PMID:


  65. Susan Graham, Deborah Estrin, Eric Horvitz, Isaac Kohane, Elizabeth Mynatt, Ida Sim.. Information Technology research challenges for healthcare: from discovery to delivery. ACM SIGHIT Record 2011. PMID:


  66. Bhavnani SK, Carini S, Ross J, Sim I.. Network analysis of clinical trials on depression: implications for comparative effectiveness research. AMIA ... Annual Symposium proceedings. AMIA Symposium 2010. PMID: 21346939


  67. Estrin D, Sim I.. Health care delivery. Open mHealth architecture: an engine for health care innovation. Science (New York, N.Y.) 2010. PMID: 21051617


  68. Kiritchenko S, de Bruijn B, Carini S, Martin J, Sim I.. ExaCT: automatic extraction of clinical trial characteristics from journal publications. BMC medical informatics and decision making 2010. PMID: 20920176


  69. Tu SW, Peleg M, Carini S, Bobak M, Ross J, Rubin D, Sim I.. A practical method for transforming free-text eligibility criteria into computable criteria. Journal of biomedical informatics 2010. PMID: 20851207


  70. Ross J, Tu S, Carini S, Sim I.. Analysis of eligibility criteria complexity in clinical trials. Summit on translational bioinformatics 2010. PMID: 21347148


  71. Wynden R, Weiner MG, Sim I, Gabriel D, Casale M, Carini S, Hastings S, Ervin D, Tu S, Gennari JH, Anderson N, Mobed K, Lakshminarayanan P, Massary M, Cucina RJ.. Ontology mapping and data discovery for the translational investigator. Summit on translational bioinformatics 2010. PMID: 21347152


  72. Sim I, Carini S, Tu S, Wynden R, Pollock BH, Mollah SA, Gabriel D, Hagler HK, Scheuermann RH, Lehmann HP, Wittkowski KM, Nahm M, Bakken S.. The human studies database project: federating human studies design data using the ontology of clinical research. Summit on translational bioinformatics 2010. PMID: 21347149


  73. Weng C, Tu SW, Sim I, Richesson R.. Formal representation of eligibility criteria: a literature review. Journal of biomedical informatics 2009. PMID: 20034594


  74. Carini S, Pollock BH, Lehmann HP, Bakken S, Barbour EM, Gabriel D, Hagler HK, Harper CR, Mollah SA, Nahm M, Nguyen HH, Scheuermann RH, Sim I.. Development and evaluation of a study design typology for human research. AMIA ... Annual Symposium proceedings. AMIA Symposium 2009. PMID: 20351827


  75. Moja LP, Moschetti I, Nurbhai M, Compagnoni A, Liberati A, Grimshaw JM, Chan AW, Dickersin K, Krleza-Jeric K, Moher D, Sim I, Volmink J.. Compliance of clinical trial registries with the World Health Organization minimum data set: a survey. Trials 2009. PMID: 19624821


  76. Bernstam EV, Hersh WR, Johnson SB, Chute CG, Nguyen H, Sim I, Nahm M, Weiner MG, Miller P, DiLaura RP, Overcash M, Lehmann HP, Eichmann D, Athey BD, Scheuermann RH, Anderson N, Starren J, Harris PA, Smith JW, Barbour E, Silverstein JC, Krusch DA, Nagarajan R, Becich MJ, CTSA Biomedical Informatics Key Function Committee.. Synergies and distinctions between computational disciplines in biomedical research: perspective from the Clinical andTranslational Science Award programs. Academic medicine : journal of the Association of American Medical Colleges 2009. PMID: 19550198


  77. Bernstam EV, Hersh WR, Sim I, Eichmann D, Silverstein JC, Smith JW, Becich MJ.. Unintended consequences of health information technology: a need for biomedical informatics. Journal of biomedical informatics 2009. PMID: 19508898


  78. Sim I, Chute CG, Lehmann H, Nagarajan R, Nahm M, Scheuermann RH.. Keeping raw data in context. Science (New York, N.Y.) 2009. PMID: 19197039


  79. Karp PD, Sherlock G, Gerlt JA, Sim I, Paulsen I, Babbitt PC, Laderoute K, Hunter L, Sternberg P, Wooley J, Bourne PE.. Changes to NIH grant system may backfire. Science (New York, N.Y.) 2008. PMID: 19023064


  80. Hernandez ME, Carini S, Storey MA, Sim I.. An interactive tool for visualizing design heterogeneity in clinical trials. AMIA ... Annual Symposium proceedings. AMIA Symposium 2008. PMID: 18998925


  81. de Bruijn B, Carini S, Kiritchenko S, Martin J, Sim I.. Automated information extraction of key trial design elements from clinical trial publications. AMIA ... Annual Symposium proceedings. AMIA Symposium 2008. PMID: 18999067


  82. Speedie SM, Taweel A, Sim I, Arvanitis TN, Arvanitis T, Delaney B, Peterson KA.. Characterizing primary care research: PCROM versus BRIDG. AMIA ... Annual Symposium proceedings. AMIA Symposium 2008. PMID: 18998919


  83. Speedie SM, Taweel A, Sim I, Arvanitis TN, Delaney B, Peterson KA.. The Primary Care Research Object Model (PCROM): a computable information model for practice-based primary care research. Journal of the American Medical Informatics Association : JAMIA 2008. PMID: 18579829


  84. Ghersi D, Clarke M, Berlin J, Gülmezoglu A, Kush R, Lumbiganon P, Moher D, Rockhold F, Sim I, Wager E.. Reporting the findings of clinical trials: a discussion paper. Bulletin of the World Health Organization 2008. PMID: 18568282


  85. Sim I.. Trial registration for public trust: making the case for medical devices. Journal of general internal medicine 2008. PMID: 18095047


  86. Krleza-Jeric K, Chan AW, Dickersin K, Sim I, Grimshaw J, Gluud C, en nombre del grupo de Ottawa.. [Principles of the international registry of protocols and clinical trial results based on health interventions in human beings: Ottawa Declaration (part 1)]. Revista panamericana de salud publica = Pan American journal of public health 2006. PMID: 16968596


  87. Sim I, Chan AW, Gülmezoglu AM, Evans T, Pang T.. Clinical trial registration: transparency is the watchword. Lancet (London, England) 2006. PMID: 16714166


  88. Chan AW, Sim I, Gülmezoglu AM, Unterlerchner P, Karam G, Pang T.. Assessing clinical trial results. Science (New York, N.Y.) 2006. PMID: 16634140


  89. Gülmezoglu AM, Sim I.. International clinical trial registration: any progress? Wiener klinische Wochenschrift 2006. PMID: 16489516


  90. Berlin A, Sorani M, Sim I.. A taxonomic description of computer-based clinical decision support systems. Journal of biomedical informatics 2006. PMID: 16442854


  91. Rubin DL, Lewis SE, Mungall CJ, Misra S, Westerfield M, Ashburner M, Sim I, Chute CG, Solbrig H, Storey MA, Smith B, Day-Richter J, Noy NF, Musen MA.. National Center for Biomedical Ontology: advancing biomedicine through structured organization of scientific knowledge. Omics : a journal of integrative biology 2006. PMID: 16901225


  92. Olasov B, Sim I.. RuleEd, a web-based semantic network interface for constructing and revising computable eligibility rules. AMIA ... Annual Symposium proceedings. AMIA Symposium 2006. PMID: 17238670


  93. Sim I, Detmer DE.. Beyond trial registration: a global trial bank for clinical trial reporting. PLoS medicine 2005. PMID: 16220999


  94. Miller RH, West C, Brown TM, Sim I, Ganchoff C.. The value of electronic health records in solo or small group practices. Health affairs (Project Hope) 2005. PMID: 16162555


  95. Krleza-Jeric K, Chan AW, Dickersin K, Sim I, Grimshaw J, Gluud C.. Principles for international registration of protocol information and results from human trials of health related interventions: Ottawa statement (part 1). BMJ (Clinical research ed.) 2005. PMID: 15845980


  96. Sim I, Cummings SR.. Quantifying the gap between proof and practice. Evidence-based cardiovascular medicine 2004. PMID: 16379955


  97. Miller RH, Sim I.. Physicians' use of electronic medical records: barriers and solutions. Health affairs (Project Hope) 2004. PMID: 15046136


  98. Berlin A, Sorani M, Sim I.. Characteristics of outpatient clinical decision support systems: a taxonomic description. Studies in health technology and informatics 2004. PMID: 15360878


  99. Miller RH, Sim I, Newman J.. Electronic medical records in solo/small groups: a qualitative study of physician user types. Studies in health technology and informatics 2004. PMID: 15360895


  100. Cuadros J, Sim I.. EyePACS: an open source clinical communication system for eye care. Studies in health technology and informatics 2004. PMID: 15360804


  101. Sim I, Carini S, Olasov B, Jeng S.. Trial bank publishing: phase I results. Studies in health technology and informatics 2004. PMID: 15361060


  102. Sim I, Cummings SR.. A new framework for describing and quantifying the gap between proof and practice. Medical care 2003. PMID: 12886168


  103. Sim I, Berlin A.. A framework for classifying decision support systems. AMIA ... Annual Symposium proceedings. AMIA Symposium 2003. PMID: 14728243


  104. Carini S, Sim I.. SysBank: a knowledge base for systematic reviews of randomized clinical trials. AMIA ... Annual Symposium proceedings. AMIA Symposium 2003. PMID: 14728309


  105. Sim I, Olasov B, Carini S.. The Trial Bank system: capturing randomized trials for evidence-based medicine. AMIA ... Annual Symposium proceedings. AMIA Symposium 2003. PMID: 14728579


  106. Sim I, Sanders GD, McDonald KM.. Evidence-based practice for mere mortals: the role of informatics and health services research. Journal of general internal medicine 2002. PMID: 11972727


  107. Linder JA, Sim I.. Antibiotic treatment of acute bronchitis in smokers: a systematic review. Journal of general internal medicine 2002. PMID: 11929510


  108. Sim I, Owens DK, Lavori PW, Rennels GD.. Electronic trial banks: a complementary method for reporting randomized trials. Medical decision making : an international journal of the Society for Medical Decision Making 2000. PMID: 11059477


  109. Sim I, Lavori P.. Meta-analyses and large randomized, controlled trials. The New England journal of medicine 1998. PMID: 9424568


  110. Sim I, McDonald KM, Lavori PW, Norbutas CM, Hlatky MA.. Quantitative overview of randomized trials of amiodarone to prevent sudden cardiac death. Circulation 1997. PMID: 9386144


  111. Sim I, Hlatky MA.. Growing pains of meta-analysis. BMJ (Clinical research ed.) 1996. PMID: 8819428


  112. Sim I, Rennels G.. A trial bank model for the publication of clinical trials. Proceedings. Symposium on Computer Applications in Medical Care 1995. PMID: 8563415


  113. Burcham TS, Sim I, Bolin LM, Shooter EM.. The NGF complex from the African rat Mastomys natalensis. Neurochemical research 1991. PMID: 1791910


  114. Manchand PS, Cerruti RL, Martin JA, Hill CH, Merrett JH, Keech E, Belshe RB, Connell EV, Sim IS.. Synthesis and antiviral activity of metabolites of rimantadine. Journal of medicinal chemistry 1990. PMID: 2362279


  115. Lepock JR, Cheng KH, Al-Qysi H, Sim I, Koch CJ, Kruuv J.. Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1987. PMID: 3036971


  116. Frankfurt M, Siegel RA, Sim I, Wuttke W.. Estrous cycle variations in cholecystokinin and substance P concentrations in discrete areas of the rat brain. Neuroendocrinology 1986. PMID: 2419781


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